The gynecomastia treatment usually includes the surgical intervention, although depending on the degree of genecomastia or the age of the patient the specialist can opt for a treatment without surgery.

When there is an underlying cause, including nutritional factors, use of drugs or certain drugs, the suspension of these behaviors can lead to the regression of gynecomastia in a few weeks. If this improvement does not occur or if the use of the drug can not be suspended, it will be the specialist who will determine, according to the degree of gynecomastia and age of the patient, the most opportune treatment to eliminate gynecomastia.

If gynecomastia has developed due to excess estrogen in the body, medical treatment will aim to block or reduce the production of estrogen in breast tissue. Anti-estrogens such as tamoxifen, raloxifene and clomiphene can be efficient for a possible blockage of production.

However, there are few well-documented prospective studies to conclusively determine the efficacy of drug treatments in the treatment of gynecomastia. The duration of gynecomastia is the most relevant factor when determining the start and type of treatment. The benefits of treatments, which do not include surgery, in men with gynecomastia in the late fibrotic phase (duration greater than or equal to 12 months) are ineffective. The treatments without surgery are used in those cases in which the diagnosis of gynecomastia is early, that is, during the proliferative phase of gynecomastia.

How to reduce gynecomastia without surgery

Tamoxifen for reducing gyno without surgery

The treatment of gynecomastia with tamoxifen is effective in gynecomastia of recent appearance. This medication is an estrogen antagonist that acts by blocking its effect in all tissues, including the breast, which is commonly used as a chemotherapeutic agent in breast cancer. In the acute and proliferative phase of gynecomastia, this medication is usually used effectively, although if there is no regression after one year, surgery will be required to eliminate gynecomastia.. In recent studies in men with gynecomastia due to several causes, tamoxifen was used for 3 to 9 months, reaching in 90% of cases a reduction of gynecomastia. This drug does not usually produce side effects, although in some cases the appearance of epigastric discomfort and nausea has been confirmed. However, a medical recommendation in the area of ??gynecomastia treatment is mandatory for its consumption.

Raloxifen to reduce gynecomastia without surgery

This is another selective modulator of estrogen receptors related to tamoxifen. A greater efficacy of raloxifene treatment in breast reduction has been demonstrated in the majority of young people with persistent pubertal gynecomastia. It is considered, however, that the data are insufficient to recommend its use.

Clomifeno for male breast treatment without surgery

It is a weak synthetic estrogen with anti-estrogenic action that binds to estrogen receptors, thus blocking the binding of circulating estrogens. It stimulates the hypothalamic-pituitary axis, increasing the production of gonadotropins, which leads to the increase of testosterone and estrogen.
The results were less promising than those obtained with tamoxifen. With clomiphene a partial reduction is observed in 50% of the individuals and a complete remission in only 20%. Adverse effects are rare and include visual changes, rash, dizziness, headache and nausea.

Testolactone to reduce gynecomastia without surgery

It is an aromatase inhibitor, blocking the formation of estrogen. It was used, with variable success, in doses of 150mg per day, for 6 months. Some independent studies consider testolactone as a beneficial medication in the treatment of gynecomastia , although less effective than treatment with tamoxifen. It can cause, as a side effect, nausea, vomiting, edema and aggravation of hypertension.

Anaztrazol for reducing gyno without surgery

It is an aromatase inhibitor that was not better than the effect, according to a study with 80 children with gynecomastia, so it is not recommended in pubertal gynecomastia. Also in men with prostate cancer, with gynecomastia associated with the use of bicalutamide, tamoxifen was significantly more effective than anastrazole in reducing pain or hypersensitivity mammary and gynecomastia.

Danazol for male breast treatment without surgery

It is a synthetic derivative of testosterone that inhibits the secretion of LH and FSH, thus decreasing the testicular secretion of estradiol. Adverse effects include weight gain, acne, cannons, fluid retention, nausea, alterations in liver function parameters or even carcinoma, and should not be used for more than 6 months.